HEREDITARY KERATOSIS or TYLOSIS PALMAe

Tylosis and Oesophageal Carcinoma

structure of the epidermis of those areas of skin subject to tylosis, and we suggest that both tissues may be responsive to the same functional requirement-namely, the need to provide resistance to mechanical friction. Human epidermis can be classified into "thick" and "thin" types.3 Thick skin is found most characteristically on the palms and soles, and relative to thin skin it has a thicker s...

Hereditary chin trembling or hereditary chin myoclonus?

Hereditary chin trembling is a rare autosomal dominant disease often considered as an "essential tremor variant". The clinical and neurophysiological data obtained in a new white family lead to the suggestion that this abnormal involuntary movement is a focal variant of hereditary essential myoclonus.

Pseudopseudohypoparathyroidism or Albright Hereditary Osteodistrophy..

Introduction: pseudohypoparathyroidism (PHP) is hormone resistance syndrome described for the first time in 1942 by Albright et al. All this patients had high levels of the PTH and specific skeletal deformities which were later termed as Albright hereditary osteodystrophy (AHO). The PTH requires the alpha subunit of G protein for its action. GNAS1 gene encodes the alpha subunit of the G protein...

Inverted follicular keratosis = نارقتلا يبارجلا بولقملا INVERTED FOLLICULAR KERATOSIS

Keratosis Pharyngis

Mrs. Q. M. M., 30, noticed " spots " on her throat and tongue four months ago. She was and is quite well: " the tongue felt uncomfortable " and she then saw the spots more or less as they are now?prominent, irregular, greyish masses on either tonsil, mainly round the crypta magna, on the posterior part of the tongue and on the back wall of the pharynx. Some are fully 1 cm. long, others much sma...